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. 2022 Oct 12;9:rbac079. doi: 10.1093/rb/rbac079

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© The Author(s) 2022. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Applications of vascularized liver tissue. (a) Transplanted liver tissue into the liver-injured rats. Adapted with permission from Ref. [75]. (b) Drug cytotoxicity analysis. (b_i) Vascularized hepatic lobular organoids for drug cytotoxicity analysis. Adapted with permission from Ref. [170]. (b_ii) Mechanism of action of several known hepatotoxic drugs and one experimental compound. Adapted with permission from Ref. [66]. (c) Disease models. (c_i) Liver fibrosis model. Adapted with permission from Ref. [82] (c_ii) Cancer model [209]. (c_iii) Virus transfection model. Adapted with permission from Ref. [210].