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. 2022 Oct 7;16(11):756–767. doi: 10.1111/crj.13549

TABLE 1.

Baseline characteristics of children with Mycoplasma pneumoniae pneumonia

Characteristics MRMP n = 356 (100) MSMP n = 98 (100) P MRMP * n = 285 (100) MSMP * n = 72 (100) P P a P b
Sex (male/female) 163/193 58/40 0.019 144/141 23/49 0.005 0.234 <0.001
Mean age (years) 7.34 ± 3.47 5.28 ± 4.35 <0.001 7.47 ± 3.30 5.17 ± 4.35 <0.001 0.624 0.887
Age (years) <0.001 <0.001 0.722 0.888
≤2 28 (7.9) 34 (34.7) 16 (5.6) 27 (37.5)
3–5 83 (23.3) 22 (22.4) 67 (23.5) 13 (18.1)
6–11 204 (57.3) 33 (33.7) 170 (59.6) 24 (33.3)
≥12 41 (11.5) 9 (9.2) 32 (11.2) 8 (11.1)
Total febrile day before admission (day) 5.43 ± 3.02 3.54 ± 2.90 <0.001 5.83 ± 2.83 3.78 ± 2.76 <0.001 0.098 0.495
Daily center/kindergarten, n (%) 283 (99.3) 57 (79.2) <0.001
Sibling, n (%) 274 (96.1) 49 (68.1) <0.001
Segmental or lobar pneumonia 256 (72.0) 45 (45.9) <0.001 251 (88.1) 42 (58.3) <0.001 <0.001 0.110
Antibiotics medication
Initial antibiotics, n (%) 335 (94.1) 91 (92.9) 0.650 284 (99.6) 70 (97.2) 0.007 <0.001 0.183
Prescribed antibiotics, n (%)
Macrolide
Macrolide alone 102 (28.7) 27 (27.6) 0.831 85 (29.8) 20 (27.8) 0.427 <0.001 0.554
Macrolide + cephalosporin 61 (17.1) 24 (24.5) 0.098 58 (20.4) 2 (2.8) <0.001 0.298 <0.001
Macrolide + β‐lactams 55 (15.4) 7 (7.1) 0.034 28 (9.8) 24 (33.3) <0.001 0.003 <0.001
Tetracycline or quinolone 72 (20.2) 11 (11.2) 0.041 65 (22.8) 11 (15.3) 0.107 0.439 0.492

Note: Values are presented as numbers (%) and mean ± standard deviation. Numbers in bold indicate significant differences (P < 0.05). Scale variables were analyzed using the chi‐squared test or Fisher exact test, and continuous variables were analyzed using Student's t‐test or Mann–Whitney U‐test.

Abbreviations: MRMP, macrolide‐resistant M. pneumoniae; MRMP*, macrolide‐resistant M. pneumoniae with admission; MSMP, macrolide‐susceptible M. pneumoniae; MSMP*, macrolide‐susceptible M. pneumoniae with admission; NA, not evaluated.

a

Compared with MRMP and MRMP*.

b

Compared with MSMP and MSMP*.