TABLE 1.
Characteristics | MRMP n = 356 (100) | MSMP n = 98 (100) | P | MRMP * n = 285 (100) | MSMP * n = 72 (100) | P | P a | P b |
---|---|---|---|---|---|---|---|---|
Sex (male/female) | 163/193 | 58/40 | 0.019 | 144/141 | 23/49 | 0.005 | 0.234 | <0.001 |
Mean age (years) | 7.34 ± 3.47 | 5.28 ± 4.35 | <0.001 | 7.47 ± 3.30 | 5.17 ± 4.35 | <0.001 | 0.624 | 0.887 |
Age (years) | <0.001 | <0.001 | 0.722 | 0.888 | ||||
≤2 | 28 (7.9) | 34 (34.7) | 16 (5.6) | 27 (37.5) | ||||
3–5 | 83 (23.3) | 22 (22.4) | 67 (23.5) | 13 (18.1) | ||||
6–11 | 204 (57.3) | 33 (33.7) | 170 (59.6) | 24 (33.3) | ||||
≥12 | 41 (11.5) | 9 (9.2) | 32 (11.2) | 8 (11.1) | ||||
Total febrile day before admission (day) | 5.43 ± 3.02 | 3.54 ± 2.90 | <0.001 | 5.83 ± 2.83 | 3.78 ± 2.76 | <0.001 | 0.098 | 0.495 |
Daily center/kindergarten, n (%) | 283 (99.3) | 57 (79.2) | <0.001 | |||||
Sibling, n (%) | 274 (96.1) | 49 (68.1) | <0.001 | |||||
Segmental or lobar pneumonia | 256 (72.0) | 45 (45.9) | <0.001 | 251 (88.1) | 42 (58.3) | <0.001 | <0.001 | 0.110 |
Antibiotics medication | ||||||||
Initial antibiotics, n (%) | 335 (94.1) | 91 (92.9) | 0.650 | 284 (99.6) | 70 (97.2) | 0.007 | <0.001 | 0.183 |
Prescribed antibiotics, n (%) | ||||||||
Macrolide | ||||||||
Macrolide alone | 102 (28.7) | 27 (27.6) | 0.831 | 85 (29.8) | 20 (27.8) | 0.427 | <0.001 | 0.554 |
Macrolide + cephalosporin | 61 (17.1) | 24 (24.5) | 0.098 | 58 (20.4) | 2 (2.8) | <0.001 | 0.298 | <0.001 |
Macrolide + β‐lactams | 55 (15.4) | 7 (7.1) | 0.034 | 28 (9.8) | 24 (33.3) | <0.001 | 0.003 | <0.001 |
Tetracycline or quinolone | 72 (20.2) | 11 (11.2) | 0.041 | 65 (22.8) | 11 (15.3) | 0.107 | 0.439 | 0.492 |
Note: Values are presented as numbers (%) and mean ± standard deviation. Numbers in bold indicate significant differences (P < 0.05). Scale variables were analyzed using the chi‐squared test or Fisher exact test, and continuous variables were analyzed using Student's t‐test or Mann–Whitney U‐test.
Abbreviations: MRMP, macrolide‐resistant M. pneumoniae; MRMP*, macrolide‐resistant M. pneumoniae with admission; MSMP, macrolide‐susceptible M. pneumoniae; MSMP*, macrolide‐susceptible M. pneumoniae with admission; NA, not evaluated.
Compared with MRMP and MRMP*.
Compared with MSMP and MSMP*.