FIGURE 1.

Expression levels of IL‐25/IL‐17BR in IPF lungs. Shown is immunohistochemical staining for IL‐25 (A and B) and IL‐17BR (C and D) in lung sections of IPF patients and normal controls. (A) In normal lung, positive staining for IL‐25 is observed in alveolar epithelial cells (red arrows). (B) In IPF lung, strong immuno‐reactivity for IL‐25 is showed in shedding alveolar epithelial cells (red arrows) and less intensively in fibroblasts within fibrotic foci (red scoops). Immuno‐staining is also obviously associated with infiltrated lymphocytes (red squares). (C) In normal lung, positive staining for IL‐17BR is occasionally observed in alveolar epithelial cells (red arrows). (D) In IFP lung, IL‐17BR staining is also observed in alveolar epithelial cells, fibroblasts and infiltrated lymphocytes as IL‐25. Scale bars indicate 100 μm. Abbreviations: IL, interleukin; IPF, idiopathic pulmonary fibrosis