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. 2022 Apr 11;12(6):1547–1556. doi: 10.1016/j.jceh.2022.03.012

Table 9.

Some Causes of Late (>1 year Post Transplant) Abnormalities of Liver Tests.

Some causes of late (>1 year) abnormalities of liver tests
Primary graft damage
Immune mediated rejection (T cell mediated, antibody mediated)
Infections (especially viral hepatitis A, B C or E), CMV
Recurrent disease
Drug induced liver injury
Malignancy
Abscess
Graft fibrosis and cirrhosis
Veno-occlusive disease
Graft damage secondary to vascular causes
 Hepatic artery thrombosis/stenosis
 Hepatic venous thrombosis/stenosis
 Secondary to venous outflow obstruction
Graft damage secondary to biliary causes
 Biliary strictures
 Bacterial cholangitis
 Ischaemic cholangiopathy (especially with grafts from donors after circulatory death)
Systemic diseases

CMV, Cytomegalovirus.