Table 9.
Some Causes of Late (>1 year Post Transplant) Abnormalities of Liver Tests.
| Some causes of late (>1 year) abnormalities of liver tests |
|---|
| Primary graft damage |
| Immune mediated rejection (T cell mediated, antibody mediated) |
| Infections (especially viral hepatitis A, B C or E), CMV |
| Recurrent disease |
| Drug induced liver injury |
| Malignancy |
| Abscess |
| Graft fibrosis and cirrhosis |
| Veno-occlusive disease |
| Graft damage secondary to vascular causes |
| Hepatic artery thrombosis/stenosis |
| Hepatic venous thrombosis/stenosis |
| Secondary to venous outflow obstruction |
| Graft damage secondary to biliary causes |
| Biliary strictures |
| Bacterial cholangitis |
| Ischaemic cholangiopathy (especially with grafts from donors after circulatory death) |
| Systemic diseases |
CMV, Cytomegalovirus.