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. 2022 Sep 22;14(11):1278–1285. doi: 10.1038/s41557-022-01035-7

Fig. 5. Polar residues line the cavity in nucleoporin FG fibrils.

Fig. 5

The cavity of Nup98FG85 fibril pm1 is compared with the cavities in the disease-associated fibrils of α-synuclein (PDB ID: 6XYO) and amyloid-β (PDB ID: 6SHS). Hydrophobic/aromatic residues (LIVWFYHMA) are shown in orange, polar residues (STQN) in magenta and charged residues in blue (KR) and red (ED), respectively.