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. 2022 Sep 15;395(12):1477–1507. doi: 10.1007/s00210-022-02287-3

Table 2.

Summary table on established and experimental therapies for retinal diseases

Retinal diseases Established and experimental therapies*
Diabetic retinopathy (DR)

• Blood sugar and blood pressure control to prevent DR

• Laser photocoagulation to reduce neovascularization

• Injection of anti-VEGF to prevent vascular leakage

• Eye surgery to remove partial vitreous humor

• Chronic steroid supplementation

Age-related macular degeneration (AMD)

• Intravitreal injection of anti-VEGF medicines (ranibizumab, aflibercept, and brolucizumab) to treat wet AMD

• Oral supplements of vitamins

• Photodynamic therapy (PDT) destroys the abnormal blood vessels that cause wet AMD

Glaucoma

• Prescription eyedrops (prostaglandins, beta blockers, alpha-adrenergic agonists, carbonic anhydrase inhibitors, rho kinase inhibitors, miotic or cholinergic agents) to decrease eye pressure

• Oral medications, usually a carbonic anhydrase inhibitor

• Laser trabeculoplasty to treat open-angle glaucoma

• Trabeculectomy to remove part of the trabecular meshwork

• Drainage tubes to lower eye pressure

• Minimally invasive glaucoma surgery to lower eye pressure

• Laser peripheral iridotomy to treat acute angle-closure glaucoma

• Cell transplantation to repair or replace damaged retinal tissues. *