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. 2022 Sep 16;65(12):2132–2145. doi: 10.1007/s00125-022-05789-0

Table 4.

Summary of findings in offspring at 12 months of age

Variable Male offspring Female offspring
Ob
vs Con
Ob-Met
vs Con
Ob-Met
vs Ob
Con
vs Ob
Con vs
Ob-Met
Ob vs
Ob-Met
Adipose tissue
 Adiposity ↑↑
 Hypertrophy
 Hyperplasia
 Inflammation ↑↑
Liver
 Hepatomegaly (↑)
 Lipid accumulation
Serum
 Insulin
 Leptin

This table summarises the sex-specific findings presented in the current manuscript

↑, upregulated; ↑↑, further upregulated; ↔, unchanged; arrows within parentheses indicate changes that do not reach statistical significance (0.05<p<0.1)