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. 2022 Nov 3;7:66. doi: 10.1038/s41536-022-00254-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a ROS content in IL-1β-induced chondrocytes administrated with nanofiber membranes was evaluated by flow cytometry. b The expression of antioxidative related genes, including Cat, Gss, and Sod1, in Il-1β induced chondrocytes treated with nanofiber membranes. c Expression of antioxidative factors, including GSH, CAT, and SOD, in Il-1β-induced chondrocytes treated with nanofiber membranes, was detected by ELISA. d Expression of GSH, SOD1, and NRF2 in Il-1β-induced chondrocytes treated with nanofiber membranes was detected by immunofluorescence staining. (Scale bars, 100 µm and 20 µm). The values were presented as mean ± SD (n = 3; statistics: one-way ANOVA; *^{, #} means p < 0.05, **^{, ##} means p < 0.01, ***^{, ###} means p < 0.001, * is the statistical difference compare with P and ^# is the statistical difference between the pairwise comparison).