Table 1.
Demographics and disease characteristics of patients with early-stage NSCLC, non-malignant pulmonary diseases, and healthy controls at study enrollment and after quality control (QC) assessment.
| Characteristics | Early NSCLC | Non-malignant pulmonary diseases | Healthy controls | |||
|---|---|---|---|---|---|---|
| At enrollment N = 76 (%) |
After QC N = 63 (%) |
At enrollment N = 12 (%) |
After QC N = 10 (%) |
At enrollment N = 53 (%) |
After QC N = 44 (%) |
|
| Age, n (%) | ||||||
| ≥ 60 year | 61 (80.3) | 49 (77.8) | 8 (66.7) | 7 (70) | 10 (18.9) | 9 (20.5) |
| < 60 year | 15 (19.7) | 14 (22.2) | 4 (33.3) | 3 (30) | 43 (81.1) | 35 (79.5) |
| Sex, n (%) | ||||||
| Male | 38 (50) | 29 (46.0) | 3 (25) | 3 (30) | 19 (35.8) | 15 (34.1) |
| Female | 38 (50) | 34 (54.0) | 9 (75) | 7 (70) | 34 (64.2) | 29 (65.9) |
| Smoking, n (%) | ||||||
| Current | 4 (5.3) | 4 (6.3) | 0 | 0 | 3 (5.7) | 2 (4.5) |
| Former | 23 (30.3) | 19 (30.2) | 0 | 0 | 2 (3.8) | 2 (4.5) |
| Never | 45 (59.2) | 36 (57.1) | 10 (83.3) | 9 (90) | 46 (86.8) | 38 (86.5) |
| Unknown | 4 (5.3) | 4 (6.3) | 2 (16.7) | 1 (10) | 2 (3.8) | 2 (4.5) |
| Histology malignancy, n (%) | ||||||
| Adenocarcinoma | 75 (98.7) | 62 (98.4) | N/A | N/A | N/A | N/A |
| Squamous carcinoma | 1 (1.3) | 1 (1.6) | ||||
| Histology non-malignancy, n (%) | ||||||
| Granulomatous inflammation | N/A | N/A | 3 (25) | 3 (30) | N/A | N/A |
| Chronic and acute inflammation | 5 (41.8) | 4 (40) | ||||
| Sclerosing pneumocytoma | 1 (8.3) | 1 (10) | ||||
| Benign Calcified nodule | 1 (8.3) | 1 (10) | ||||
| Pulmonary harmatoma | 1 (8.3) | 1 (10) | ||||
| Aneurysm of blood vessel | 1 (8.3) | 0 | ||||
| Staging by AJCC | ||||||
| 0 (TisN0M0) | 4 (5) | 4 (6) | ||||
| IA | 31 (41) | 26 (41) | N/A | N/A | N/A | N/A |
| IB | 18 (24) | 14 (22) | ||||
| IIA | 8 (10) | 6 (10) | ||||
| IIB | 6 (8) | 6 (10) | ||||
| IIIA | 7 (9) | 5 (8) | ||||
| IIIB | 2 (3) | 2 (3) | ||||
QC quality control, N/A non-applicable.