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. 2022 Nov 2;13:6565. doi: 10.1038/s41467-022-34323-4

Table 1.

Trans-disease meta-analysis results for loci meeting criteria

Marker ID Chr Position (hg19) Alleles (risk/non-risk)b TDMA Direction Meta-analysis P-values Meta-analysis Odds ratios Risk allele frequenciesa Nearby genes
Psoriasis CAD TDMA Psoriasis CAD TDMA Psoriasis CAD
rs6430076 2 145797185 G/A Opposing 8.2 × 10−5 1.8 × 10−6 1.6 × 10−8 0.92 1.05 1.07 0.35 0.32 TEX41, ZEB2
rs1990760 2 163124051 T/C Shared 5.7 × 10−15 5.3 × 10−5 1.3 × 10−18 1.16 1.04 1.10 0.61 0.56 IFIH1
rs76151170 12 56659320 C/T Shared 9.8 × 10−16 6.0 × 10−5 2.8 × 10−19 1.38 1.09 1.23 0.94 0.94 IL23A. COQ10A
rs12979495 19 10964632 G/A Shared 1.3 × 10−5 4.7 × 10−10 2.5 × 10−11 1.10 1.07 1.08 0.74 0.75 DNM2, ILF3

Chr chromosome, OR odds ratio, p p-value, CAD coronary artery disease.

aAllele frequencies are provided for each entire meta-analysis (cases and controls), rather than specifically for each disease.

bRisk allele corresponds to TDMA. Gene names are italicized.