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. 2022 Jun 18;47(13):2300–2308. doi: 10.1038/s41386-022-01359-5

Table 2.

Multivariable models.

Coefficient (95% CI) Wald's Chi-square p-value
(a) Multivariable model assessing the association between baseline factors and day-of-injury (log)GFAP levels.
Age 0.007 (0.002, 0.012) 8.61 0.003
Sex Female vs Male −0.288 (−0.464, −0.113) 10.35 0.001
Race 3.07 0.215
 Black vs White −0.178 (−0.404, 0.049)
 Other vs White 0.103 (−0.232, 0.439)
Hispanic Yes vs No −0.092 (−0.308, 0.124) 0.7 0.404
Injury cause Violence vs Incident/other −0.391 (−0.719, −0.064) 5.49 0.019
Psychiatric history Yes vs No −0.216 (−0.408, −0.024) 4.85 0.028
Prior TBI Yes vs No −0.283 (−0.458, −0.109) 10.1 0.001
CT + vs − 1.610 (1.431, 1.789) 309.7 <0.001
PTA Yes vs No 0.900 (0.704, 1.097) 80.5 <0.001
Sampling Time 32.45 <0.001
9–16h vs 0–8h 0.648 (0.424, 0.871)
17–24h vs 0–8h 0.422 (0.214, 0.630)
(b) Multivariable model assessing the association between baseline factor and day-of-injury (log)hsCRP levels.
Age 0.009 (0.005, 0.013) 18.86 <0.001
Sex Female vs Male −0.098 (−0.251, 0.055) 1.59 0.208
Race 4.01 0.134
 Black vs White 0.081 (−0.116, 0.278)
 Other vs White −0.252 (−0.544, 0.039)
Hispanic Yes vs No 0.495 (0.307, 0.682) 26.64 <0.001
Injury cause Violence vs Incident/other −0.233 (−0.518, 0.052) 2.57 0.109
Psychiatric history Yes vs No −0.184 (−0.351, -0.016) 4.63 0.031
Prior TBI Yes vs No −0.107 (−0.259, 0.045) 1.91 0.167
CT + vs − 0.321 (0.164, 0.477) 16.2 <0.001
PTA Yes vs No 0.183 (0.012, 0.354) 4.39 0.036
Sampling Time 629 <0.001
 9–16h vs 0–8h 1.384 (1.190, 1.579)
 17–24h vs 0–8h 2.307 (2.125, 2.488)
HHS Vulnerability Disclosure