Table 1.

Genetic alterations from DICS to IDC

Gene symbol	Upregulation	Downregulation	Functions	Reference
HER2		√	Unknown	14
BCL-2		√	Cell proliferation and apoptosis	15
ANAPC13		√	Cell proliferation and apoptosis	16
CLTCL1		√	Miscellaneous	16
ADFP		√	Unknown	16
ARHGAP19		√	Signal transduction	16
C-MYC	√		Unknown	17
CXCL9	√		Signal transduction	16
MED10	√		Transcriptional regulation	16
MARCH8	√		Miscellaneous	16
NOX4	√		Cell proliferation and apoptosis	16
P4HA1	√		Metabolism	16
HN1	√		Unknown	16