TABLE 1.
Characteristic | OSA-nMCIs (N = 26) | OSA-MCIs (N = 26) | HCs (N = 26) | F/H | p-Value |
Age (year) | 36.15 ± 9.48 | 39.26 ± 10.25 | 39.84 ± 11.18 | 1.66F | 0.961 |
BMI (Kg/m2) | 27.12 ± 4.00 | 27.27 ± 2.77 | 19.70 ± 0.98 | 51.48H | 0.000ab |
AHI (/h) | 54.05 ± 19.06 | 56.79 ± 24.73 | 2.35 ± 1.21 | 51.35H | 0.000ab |
Education (year) | 12.92 ± 3.17 | 11.61 ± 2.80 | 12.23 ± 3.76 | 1.59H | 0.452 |
LSaO2 (%) | 65.00 ± 11.73 | 70.65 ± 12.87 | 94.03 ± 3.25 | 52.91H | 0.000bc |
MSaO2 (%) | 90.54 ± 4.91 | 92.00 ± 3.88 | 97.11 ± 2.00 | 34.68H | 0.000bc |
Total sleep time (min) | 450.6 ± 64.38 | 436.1 ± 44.89 | 401.8 ± 12.40 | 17.40H | 0.000ab |
Sleep efficiency (%) | 0.864 ± 0.144 | 0.849 ± 0.151 | 91.13 ± 3.201 | 51.34H | 0.000bc |
N1 stage (%) | 30.51 ± 17.78 | 28.57 ± 16.69 | 10.48 ± 3.59 | 29.15H | 0.000ab |
N2 stage (%) | 39.50 ± 15.41 | 40.00 ± 12.61 | 38.99 ± 6.435 | 0.04H | 0.98 |
N3 stage (%) | 22.05 ± 18.37 | 22.62 ± 17.40 | 30.63 ± 5.38 | 11.40H | 0.003ab |
REM (%) | 7.74 ± 7.31 | 8.10 ± 8.93 | 20.46 ± 6.36 | 30.46H | 0.000ab |
SaO2 < 90% | 25.60 ± 18.35 | 25.39 ± 20.75 | 0.23 ± 0.17 | 51.01H | 0.000ab |
AI (/h) | 38.20 ± 21.91 | 36.80 ± 23.80 | 11.65 ± 2.97 | 34.26H | 0.000ab |
MOCA | 27.34 ± 1.26 | 22.84 ± 2.80 | 27.57 ± 1.67 | 49.99H | 0.000bc |
ESS | 11.61 ± 4.15 | 11.96 ± 4.13 | 3.03 ± 1.82 | 46.30H | 0.000ab |
Head movement | 0.20 ± 0.10 | 0.16 ± 0.07 | 0.11 ± 0.07 | 8.481F | 0.000ab |
BMI, body mass index, AHI, apnea hypopnea index; LSaO2, minimum blood oxygen saturation; MSaO2, average blood oxygen saturation; REM, rapid eye movement; SaO2 < 90%, percentage of total sleep time with oxygen saturation less than 90; AI, arousal index; MOCA, Montreal Cognitive Assessment; ESS, Epworth Sleepiness Scale; F, analysis of variance; H, Kruskal–Wallis test.
aSignificant difference between HCs and OSA-nMCIs in post hoc analysis.
bSignificant difference between HCs and OSA-MCIs in post hoc analysis.
cSignificant difference between OSA-nMCIs and OSA-MCIs in post hoc analysis.