Various extents of lung abnormality in four patients. Original axial CT
images (A, C, E, G) and the same CT images with a segmented
overlay of ILA (B, D, F, and H) are shown.
(A, B) Scans in a 76-year-old woman show subtle
subpleural ground-glass abnormality that accounts for 2.9% of the lung
area, indicating insignificant abnormality. (C, D) Scans in
an 84-year-old woman show ground-glass and reticular abnormalities that
account for 6.7% of the lung area, indicating significant abnormality.
(E, F) Scans in a 73-year-old woman show faint
ground-glass abnormality that accounts for 10.6% of the lung area,
indicating significant abnormality. (G, H) Scans in a
60-year-old woman show widespread ground-glass abnormality that affects
26.2% of the lung area, indicating significant abnormality. The
segmentations shown were performed manually by using 3D Slicer software
(Brigham and Women’s Hospital, Harvard Medical School, Boston,
MA).