Figure 4.

Univariate features are clinically useful. Within the eight most frequently resected regions in our dataset, spectral density is often different between the irritative zone, seizure onset zone, and the normative atlas. In each region and frequency band, we independently tested whether the median normalized band-power was different in the seizure onset zone versus the normative atlas, and the irritative zone versus the normative atlas. We completed this process for each of the following five frequency bands (delta: 0.5–4 Hz, theta: 4–8 Hz, alpha: 8–13 Hz, beta: 13–30 Hz, gamma: 30–80 Hz) and across all 20 regions. We thus Bonferroni corrected each test for 100 multiple comparisons. The asterisk above the Greek letters means the seizure onset zone is significantly different from normal, whereas the plus symbol below the letters means the irritative zone is significantly different from normal, Bonferroni corrected for 100 comparisons to α = 0.0005. The shaded area represents the interquartile interval.