Table 1.

Demographic and clinical parameters in patients with and without GI symptoms or elevated liver enzyme.

Parameters	Enrolled patients (n = 93)	GI symptoms		p-Value	Elevated liver enzyme		p-Value
		With (n = 65)	Without (n = 28)		With (n = 22)	Without (n = 71)
Age, years	58.0± 12.1	58.7 ± 11.8	56.3 ± 13.0	0.397	56.5 ± 12.6	58.4 ± 12.0	0.509
Male	46	30	16	0.331	12	34	0.585
Smoking	9	5	4	0.324	4	5	0.208
Alcohol	5	2	3	0.159	2	3	0.589
Comorbidities
None	37	26	11	0.949	9	28	0.902
Any comorbidities	56	39	17		13	43
HTN	37	26	11	0.949	9	28	0.902
DM	14	10	4	1.000	1	13	0.175
COPD	6	3	3	0.361	2	4	0.624
Cardiac disease	8	5	3	0.693	2	6	1.000
Cerebrovascular disease	8	5	3	0.693	0	8	0.191
CKD	5	5	0	0.131	1	4	1.000
CLD	6	3	3	0.361	1	5	1.000
Malignancy	1	0	1	0.301	0	1	1.000
Symptoms
Fever	73	52	21	0.590	18	55	0.774
Cough	70	51	19	0.277	18	52	0.415
Shortness of breath	53	45	8	<0.001	17	36	0.028
Fatigue	59	52	7	<0.001	18	41	0.041
Disease classification
Mild type	0	0	0	<0.001	0	0	0.016
Moderate type	42	21	21		5	37
Severe (including critical) type	51 (2)	44 (2)	7 (0)		17 (1)	34 (1)
Treatments
Antibiotics treatment	35	25	10	0.802	11	24	0.171
Antiviral treatment	90	63	27	1.000	22	68	1.000
Glucocorticoid treatment	7	6	1	0.670	5	2	0.007
Duration of disease, days	54.3± 13.4	56.4 ± 12.7	49.6 ± 14.1	0.026	59.3 ± 14.9	52.8 ± 12.6	0.046

HTN, hypertension; DM, diabetes mellitus; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; CLD, chronic liver disease.