Table 3.
The subgroup analysis of patients with and without GI symptoms.
| Parameters |
Hyporexia
/anorexia |
p-Value |
Nausea
/vomiting |
p-Value | Diarrhea | p-Value | |||
|---|---|---|---|---|---|---|---|---|---|
| With | Without | With | Without | With | Without | ||||
| Age, years | 59.0 ± 11.8 | 55.7 ± 12.7 | 0.225 | 55.6 ± 11.2 | 58.9 ± 12.4 | 0.249 | 57.6 ± 11.2 | 58.1 ± 12.6 | 0.854 |
| Male | 30 | 16 | 0.606 | 12 | 34 | 0.691 | 10 | 36 | 0.125 |
| Symptoms | |||||||||
| Fever | 50 | 23 | 0.767 | 18 | 55 | 0.176 | 22 | 51 | 0.654 |
| Cough | 49 | 21 | 0.416 | 20 | 50 | 0.818 | 22 | 48 | 0.374 |
| Shortness of breath |
44 | 9 | <0.001 | 18 | 35 | 0.137 | 20 | 33 | 0.033 |
| Fatigue | 50 | 9 | <0.001 | 21 | 38 | 0.031 | 23 | 36 | 0.005 |
| Disease classification | <0.001 | 0.082 | 0.017 | ||||||
| Mild type | 0 | 0 | 0 | 0 | 0 | 0 | |||
| Moderate type | 20 | 22 | 8 | 34 | 7 | 35 | |||
| Severe (including critical) type |
43 (2) | 8 | 18 (2) | 33 | 20 (2) | 31 | |||
| Laboratory test | |||||||||
| WBC count, × 109 cells per L | 6.0 (5.0, 7.3) | 6.1 (5.3, 7.6) | 0.318 | 6.0 (4.9, 7.8) | 6.1 (5.1, 7.4) | 0.915 | 5.2 (4.9, 6.7) | 6.1 (5.2, 7.6) | 0.061 |
| LYM count, × 109 cells per L | 1.4 (1.0, 1.7) | 1.5 (1.2, 1.8) | 0.141 | 1.5 (1.0, 1.7) | 1.4 (1.1, 1.8) | 0.726 | 1.6 (1.1, 1.8) | 1.4 (1.1, 1.8) | 0.488 |
| Neutrophil count, × 109 cells per L | 3.4 (2.7, 4.5) | 3.9 (3.0, 4.7) | 0.430 | 3.8 (2.6, 4.7) | 3.5 (2.8, 4.6) | 0.811 | 3.1 (2.6, 4.3) | 3.8 (3.0, 4.8) | 0.039 |
| HB, g/L | 116.0 (108.0, 125.0) | 123.5 (112.8, 136.5) | 0.004 | 108.5 ± 21.9 | 121.1 ± 12.8 | 0.009 | 111.8 ± 18.4 | 120.0 ± 15.5 | 0.031 |
| PLT, × 109/L | 253.0 (203.0, 339.0) | 228.0 (187.8, 283.5) | 0.155 | 297.3 ± 104.4 | 244.5 ± 83.9 | 0.013 | 234.0 (185.0, 334.0) | 254.5 (202.8, 305.5) | 0.617 |
| PT, s | 11.3 (10.9, 11.8) | 11.3 (11.0, 11.8) | 0.961 | 11.4 (11.0, 12.0) | 11.3 (10.9, 11.7) | 0.370 | 11.2 (10.8, 11.9) | 11.4 (11.0, 11.7) | 0.358 |
| APTT, s | 26.8 ± 4.4 | 26.8 ± 3.8 | 0.930 | 28.1 ± 4.4 | 26.3 ± 4.0 | 0.068 | 25.9 ± 4.2 | 27.2 ± 4.1 | 0.180 |
| FI, g/L | 2.8 (2.4, 3.4) | 2.8 (2.3, 3.4) | 0.850 | 2.8 (2.5, 3.4) | 2.9 (2.4, 3.3) | 0.969 | 2.8 (2.5, 3.0) | 2.8 (2.4, 3.8) | 0.446 |
| d-dimer, mg/L | 0.8 (0.3, 1.3) | 0.3 (0.2, 0.6) | <0.001 | 0.7 (0.3, 1.2) | 0.4 (0.3, 1.0) | 0.204 | 0.7 (0.3, 1.2) | 0.4 (0.2, 1.0) | 0.253 |
| ALT, U/L | 30.9 (19.0, 64.0) | 27.0 (16.3, 35.5) | 0.136 | 33.0 (19.0, 91.0) | 28.0 (17.0, 39.0) | 0.101 | 25.0 (17.0, 64.0) | 31.0 (18.0, 46.3) | 0.783 |
| AST, U/L | 23.0 (17.0, 35.0) | 19.5 (16.0, 23.0) | 0.126 | 24.5 (17.8, 55.3) | 20.0 (16.0, 27.0) | 0.081 | 22.0 (16.0, 35.0) | 21.0 (16.8, 27.5) | 0.599 |
| TBIL, μmol/L | 10.3 (7.9, 14.8) | 10.2 (8.1, 13.8) | 0.987 | 10.1 (7.5, 16.7) | 10.2 (8.4, 13.4) | 0.881 | 9.6 (7.2, 15.2) | 10.3 (8.8, 13.6) | 0.729 |
| ALB, g/L | 37.7 (33.9, 38.6) | 38.5 (36.7, 40.9) | 0.004 | 37.8 (35.5, 38.6) | 37.9 (34.8, 40.2) | 0.394 | 38.0 (34.9, 38.6) | 37.9 (34.7, 39.8) | 0.856 |
| Duration of disease, days | 56.7± 12.7 | 49.5 ± 13.8 | 0.015 | 58.1 ± 12.3 | 52.9 ± 13.6 | 0.094 | 59.8 ± 13.4 | 52.1 ± 12.9 | 0.012 |
WBC, white blood cell; LYM, lymphocyte; HB, Hemoglobin; PLT, platelet; PT, prothrombin time; APTT, activated partial thromboplastin time; FI, fibrinogen; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin; ALB, albumin.