Table 1.

Summary of the calculated minimal, maximal, and mean drug efficacy for TNF-α, IL-6, and IL-8. The analysis of the cytokine release allows a “yes–no” response from the co-culture for the drug efficacy, which depends on the applied drug and the analysed cytokine. Mean drug efficacy was calculated as mean ± SD for the different drugs out of in summary n = 6 wells for each group performed in three biological replicates

	TNF-α	IL-6	IL-8
Minimal drug efficacy	28% (6-MP)	9% (infliximab)	21% (6-MP)
Maximal drug efficacy	100% (infliximab)	34% (prednisolone)	58% (prednisolone)
Mean drug efficacy	60 ± 44%	19 ± 50%	41 ± 19%