Table 3.

Pair-wise group differences with the post hoc analyses

Subfields	Diffusion indices	CN versus MCI		CN versus AD		MCI versus AD
		Mean difference (CN-MCI)	Effect size (Hedge’s g)	Mean difference (CN-AD)	Effect size (Hedge’s g)	Mean difference (MCI-AD)	Effect size (Hedge’s g)
CA1–3	ODI	−0.010	−0.548	−0.037**	−1.025	−0.028**	−0.602
	VISO	−0.015	−0.554	−0.107***	−1.412	−0.092***	−0.950
	VFIC	0.007	0.435	0.017**	0.901	0.011	0.440
	VFEC	0.017	0.56	0.109***	1.359	0.092***	0.856
Subiculum	ODI	−0.001	−0.246	−0.025*	−0.757	−0.024*	−0.461
	VISO	−0.011	−0.439	−0.070***	−1.191	−0.060***	−0.782
	VFIC	0.006	0.301	0.014*	0.572	0.008	0.275
	VFEC	0.022	0.673	0.088***	1.427	0.067***	0.797
CA4-DG	ODI	−0.016	−0.633	−0.032**	−0.766	−0.016	−0.172
	VISO	−0.005	−0.498	−0.069***	−1.313	−0.064***	−0.984
	VFIC	0.010*	0.528	0.015**	0.788	0.005	0.187
	VFEC	0.004	0.49	0.073***	1.380	0.068***	0.918

AD = Alzheimer disease; CN = cognitively normal. Analysis corrected for age, sex, education, APoE  ε4 status and total intracranial volume. Bootstrap results are based on 5000 bootstrap samples. Multiple comparisons across three regions of interest (i.e. subfields) were adjusted by FDR using Benjamini-Hochberg criterion (α = 0.05).

*P_FDR < 0.05; **P_FDR < 0.01; ***P_FDR < 0.001.