Fig. 1.

Vast recombination deserts in Ae. aegypti contain thousands of genes. a–c) Chromosomes 1, 2, and 3, respectively. The X-axis is the chromosome position. The top panels are genetic distances measured in centimorgan. The lower panels are the number of protein-coding genes in the corresponding 10-Mb window. LRRs in Ae. aegypti were previously shown in all 3 chromosomes by mapping the genetic cross data (Juneja et al. 2014) to an earlier version of the assembly (Dudchenko et al. 2017; Fontaine et al. 2017). The top panels remapped the same genetic cross data to the most recent AaegL5 PacBio-based assembly (Matthews et al. 2018). On chromosome 1, the positions of the male-determining locus (M) and a GFP-expressing transgene named P10 (P, green dot, 224 Mb, Supplementary Figs. 1 and 2) are indicated. M and P showed a genetic distance of 1.02–1.55 cM according to 2 screens of 1,353 and 3,145 progenies, respectively (Table 1).