Table 2.
Overview and characteristics of intracranial EEG (iEEG) devices certified or currently in development for humans.
| Company | Device | Number of leads/contacts | ECoG sensing (N channels from N contacts) | Sample frequency (Hz) |
Stimulation Modes (A) Continuous (B) Duty cycle (C) Responsive (D) Programmable adaptive |
Rechargeable | External companion | ECoG storage on device | Evaluated in dogs with epilepsy | Current status |
|---|---|---|---|---|---|---|---|---|---|---|
| NeuroPace | RNS® system (for recording and stimulation) | 2/8 | 4/8 | 250 | (A) No (B) No (C) Yes (D) No |
No | Yes | 3,600 s | Yes | Approved for use in humans in 2013 |
| Medtronic | Percept™ (for recording and stimulation) | 2/16 | 2/16 | 250 | (A) Yes (B) Yes (C) No (D) No |
No | Yes | No LFP data | No | Approved for use in humans in 2020 |
| Medtronic | RC+S (for recording and stimulation) | 4/16 | 4/16 | 250–1,000 | (A) Yes (B) Yes (C) Yes (D) Yes |
Yes | Yes | None | Yes | Investigational device; will sunset 2022 |
| NeuroVista | SAS | 4/16 | 16/16 | 400 | (A) N/A (B) N/A (C) N/A (D) N/A |
Yes | Yes | 1 week | Yes | Dissolved SAS not available |
| CorTec | Brain Interchange One | 2/32 | 32/32 | 1,000 | (A) Yes (B) Yes (C) No (D) No |
No (requires inductive connection) | Yes | None | Yes | Investigational |
Based on the literature discussed in the text and data provided by the manufacturers. N/A, not available.