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. 2022 Nov 18;15(11):1736–1742. doi: 10.18240/ijo.2022.11.02

Figure 1. Expression levels of different factors in vitreous humor of control and PDR patients.

Figure 1

A: Altered growth factors including bFGF, PDGF-AA, GDNF, and VEGF-A in vitreous; B: Inflammatory mediators containing IL-6, -7, -8, -11, and TNF-α were detected in vitreous samples; C: Vitreous cytokines including CCL2, CXCL10, CX3CL1, CXCL1, IFN-γ, and GM-CSF were evaluated. aP<0.05, bP<0.01, PDR vs CON; cP<0.05, PDR with anti-VEGF vs PDR without anti-VEGF. CON: Control group; bFGF: Basic fibroblast growth factor; CCL2: C-C motif chemokine ligand 2; CXCL: Chemokine C-X-C ligand; CX3CL1: Fractalkine/CX3C chemokine ligand 1; GM-CSF: Granulocyte macrophage-colony stimulating factor; IL: Interleukin; IFN-γ: Interferon-γ; PDGF: Platelet-derived growth factor; PDR: Proliferative diabetic retinopathy; TNF-α: Tumor necrosis factor-α; VEGF: Vascular endothelial growth factor.