Table I.
Demographic and clinical data of herpes simplex-positive patients compared with herpes simplex-negative patients
| Parameter | HSV-positive (n = 25) | HSV-negative (n = 37) | p-value |
|---|---|---|---|
| Age, years, mean ± SD | 57.92 ± 12.91 | 54.95 ± 16.75 | 0.46 |
| Sex (male), n (%) | 9/25 (36) | 13/37 (35.14) | 0.84 |
| Positive-PMHa, n (%) | 10/25 (40) | 16/37 (43) | 0.99 |
| Time of follow up, months, mean ± SD | 34.56 ± 24.9 | 36.51 ± 27.77 | 0.78 |
| Disease involvement | |||
| Mucosa onlyb, n (%) | 6/25 (24) | 12/37 (32.43) | |
| Mucosa and skinb, n (%) | 19/25 (76) | 25/37 (67.56) | 0.67 |
a
Patients with background diseases, such as: diabetes mellitus, hypertension, hyperlipidaemia, chronic renal failure, chronic obstructive pulmonary disease (COPD), past/present oncological disease and autoimmune/rheumatic disease.
b
Disease involvement, limited to mucosa only vs mucosa and skin involvement (19/25 [76%] for HSV-positive and 25/37 [67.5%] for HSV-negative).
p-value was calculated for continuous variables using Student’s t-test, and for categorical variables using χ2 test.
HSV: herpes simplex virus; PMH: past medical history; SD: standard deviation.