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. 2022 Oct 20;12:1012391. doi: 10.3389/fonc.2022.1012391

Table 2.

Prior lines of therapy in the metastatic setting.

Variables N (%)
Median number of prior lines of therapy (range) 3 (1-7)
Prior targeted agents CDK4/6 inhibitors + AI 20 (74.1%)
CDK4/6 inhibitors + Fulvestrant 8 (29.6%)
Everolimus + AI 11 (40.7%)
Olaparib 2 (7.4%)
Prior clinical trial 2 (7.4%)
Prior cytotoxic therapy Eribulin 2 (7.4%)
Taxane 10 (37%)
Xeloda 12 (44.4%)
Gemcitabine 1 (3.7%)
Platinum 1 (3.7%)
Anthracycline 2 (7.4%)
A/C 1 (3.7%)
Prior hormonal agents Single-agent AI/SERD 9 (33.3%)

CDK4/6 inhibitors, cyclin-dependent kinase 4/6 inhibitors; AI, aromatase inhibitors; A/C, anthracycline and cyclophosphamide; SERD, selective estrogen receptor degrader.