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. 2022 Oct 18;7(43):38448–38458. doi: 10.1021/acsomega.2c03671

Table 3. Thermodynamic Parameters Determined by Colorimetric Titration of Different Ligands with FmtAΔ80.

compound enthalpy change (cal/mol) entropy change (cal/mol/K) free-energy change (cal/mol) N KD (μM)
gemifloxacin 3.9 × 104 158 –7.88 × 103 1.87 1.7
parmomycin –1.2 × 104 –15.6 –7.17 × 103 0.868 8.56
streptomycin 6.9 × 103 45.9 –6.75 × 103 1.62 11.13
tobramycin –1.0 × 106 –3360 –7.72 × 103 0.750 25.77