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. 2022 Oct 20;3:1002405. doi: 10.3389/fragi.2022.1002405

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Copyright © 2022 Zhou, Wang, Demkowicz, Johnson, Chen, Spakowicz, Zhou, Dorsett, Chen, Sodergren, Kuchel and Weinstock.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ecology richness and diversity of the microbiome. (A) Microbiome richness plot of a saliva and stool sample (*p < 0.05; **p < 0.01). (B) Microbiome Shannon diversity and inverse Simpson index plot of a saliva and stool sample. (C) Renyi diversity of the microbiome in different age groups. X-axis represents the alpha-value (increased alpha-value indicates a higher weight on dominant organisms when calculating diversity); Y-axis is the diversity index calculated based on each alpha-value (*p < 0.05. t-test with Holm-Sidak correction).