Table 2.
Early CAR T-cell toxicity | CAR T-cell patients N = 280 |
---|---|
CRS diagnosis, n (%) | 239 (85) |
CRS grade, n (%) | |
1 | 102 (43) |
2 | 125 (52) |
3 | 8 (3) |
4 | 4 (2) |
Days to maximum grade CRS, median (range) | 5 (0-12) |
Tocilizumab for CRS, n (%) | 180 (75) |
Tocilizumab doses, median (range) | 2 (1-4) |
Corticosteroids for CRS, n (%) | 118 (49) |
ICANS diagnosis, n (%) | 153 (55) |
Days to onset, median (range) | 6 (0-34) |
ICANS grade, n (%) | |
1 | 33 (22) |
2 | 34 (22) |
3 | 86 (56) |
Corticosteroids for ICANS, n (%) | 103 (67) |