Table 3.
Unadjusted and adjusted coefficients for associations between relationship dynamics and antiretroviral drug levels in hair among couples from Malawi (332 individuals nested in 211 couples)
| Explanatory variable (couple-level) | Unadjusted model Fold-effectsa, 95% CI | Adjusted modelb Fold-effects, 95% CI |
|---|---|---|
| Intimacy | 1.15 (0.62, 4.80) | 1.20 (0.39, 3.69) |
| Trust | 1.00 (0.98, 1.03) | 1.00 (0.97, 1.02) |
| Unity (“We-ness”) | 1.03 (0.92, 1.15) | 1.01 (0.91, 1.13) |
| Relationship satisfaction | 0.95 (0.79, 1.15) | 0.92 (0.76, 1.12) |
| Commitment | 0.99 (1.26, 1.59) | 1.22 (0.96, 1.54) |
| HIV treatment-specific partner support | 0.99 (0.98, 1.01) | 0.99 (0.97, 1.01) |
Hair levels were logarithmically transformed for modeling purposes because raw differences of a given magnitude have differing meanings depending on whether hair levels are high or low and differing meanings across different drugs, while relative differences of a given magnitude remain comparably meaningful in these different situations. Regression coefficients were back-transformed from the log scale to obtain fold-effects.
Multivariable models controlled for gender, age, years of education, household wealth index, relationship duration, couple HIV status, and length of time on ART.
p<0.10;
p<.05;
p<0.01;
p<0.001