. 2022 Oct 20;14:1006567. doi: 10.3389/fnagi.2022.1006567

TABLE 2.

Regression models for general cognition and domain specific cognitive functioning.

	General cognition		Memory		Executive function		Attention		Language		Visuospatial
	Z-score		Z-score		Z-score		Z-Score		Z-score		Z-score
Independent
variable	β	p	β	p	β	p	β	p	β	p	β	p
PC 1	–0.004	0.961	0.005	0.957	0.015	0.870	0.001	0.996	–0.085	0.410	0.079	0.450
PC 2	0.150	0.092	0.148	0.098	0.129	0.158	0.148	0.123	0.133	0.194	0.023	0.824
PC 3	0.325	<0.001	0.418	<0.001	0.276	0.004	0.256	0.003	0.266	0.011	0.041	0.700
PC 4	–0.097	0.281	–0.111	0.220	–0.048	0.603	–0.039	0.687	–0.137	0.179	–0.021	0.838
PC 5	0.197	0.030	0.281	0.002	0.124	0.176	0.083	0.390	0.152	0.138	0.152	0.141
PC 6	–0.126	0.159	–0.022	0.809	–0.128	0.163	–0.180	0.029	–0.042	0.682	–0.115	0.269
PC 7	0.240	0.008	0.111	0.215	0.243	0.009	0.168	0.040	0.236	0.023	0.161	0.119
Disease duration	–0.052	0.587	–0.036	0.708	0.045	0.641	0.094	0.258	–0.129	0.225	–0.128	0.230
MDS-UPDRS-III	–0.312	0.001	–0.202	0.031	–0.358	<0.001	–0.020	0.004	–0.186	0.073	–0.315	0.003
LED	–0.108	0.265	–0.064	0.508	–0.057	0.565	–0.009	0.919	–0.140	0.183	–0.103	0.352
	R²: 0.352		R²: 0.336		R²: 0.312		R²: 0.282		R²: 0.126		R²: 0.099

PC, Principal component; MDS-UPDRS-III, Movement Disorders Society–Unified Parkinson’s disease Rating Scale III; LED, Levodopa Equivalant Dose. Bold values represent significant contributors to the regression model (p < 0.05).