Table 3.

The hazard ratio (95% CI) of chronic kidney disease and hypertension in relation to dietary oxalate and oxalate-to-calcium ratio

	CKD	HTN
Dietary Ox (mg/d)
Crude	1.89 (1.25–2.85)	1.68 (1.16–2.65)
Model 1	1.79 (1.18–2.71)	1.52 (1.04–2.22)
Model 2	1.55 (0.95–2.55)	1.18 (0.77–1.83)
Model 3	2.59 (1.46–4.64)	1.79 (1.05–3.04)
Dietary Ox (mg/d)*Ca (mg/d)†
Low-Ca diet	2.43 (1.06–5.55)	2.68 (1.10–6.49)
High-Ca diet	1.72 (0.76–3.78)	1.48 (0.72–3.04)

Cox regression models were used

For CKD, model 1 was adjusted for age and sex; model 2 was additionally adjusted for systolic blood pressure, type 2 diabetes, creatinine, body mass index and smoking; model 3 was additionally adjusted for total energy intakes (kcal/d), dietary intakes of total fats (g/d), fiber (g/d)

For HTN, model 1 was adjusted for age and sex; model 2 was additionally adjusted for type 2 diabetes, eGFR, body mass index and smoking; model 3 was additionally adjusted for total energy intakes (kcal/d), dietary intakes of total fats (g/d), fiber (g/d)

Low-, and high-Ca-diet were defined according to median of Ca intakes as 1180 < and > 1180 mg/d, with a median of 990 and 1580 mg/d, respectively

^†Full model was only reported