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. 2022 Nov 3;20:501. doi: 10.1186/s12967-022-03704-0

Table 1.

Genetic correlation and polygenic overlap analyses of the SCZ and T2D

Traits Genetic correlation analysis Polygenic overlap analysis
rg ± se P P Bonferroni NSCZ ±se NT2D ±se NSCZ−T2D ±se ρ SCZ−T2D ±se rg ±se

SCZvs T2D

(EAS)

-0.054 ± 0.025 0.032 0.064 6566.74 ± 401.14 580.35 ± 273.78 665.77 ± 259.24 -0.28 ± 0.17 -0.049 ± 0.0083

SCZ vs T2D

(EUR)

-0.098 ± 0.029 0.009 0.0018 8488.47 ± 483.84 211.65 ± 205.38 1176.33 ± 244.79 -0.24 ± 0.06 -0.076 ± 0.0066