Table 1.
Summary of patient characteristics.
| Characteristics | mean | (range) |
|---|---|---|
| Age in years | ||
| Patients (N=90) | 51 | (17-71) |
| Sex | n | (%) |
| male | 56 | 60 |
| female | 34 | 40 |
| Diagnosis | ||
| Acute leukemia | 48 | 53 |
| MDS/MPN | 16 | 18 |
| NHL | 22 | 24 |
| other | 4 | 4 |
| Stage of underlying disease | ||
| early | 18 | 20 |
| intermediate | 36 | 40 |
| advanced | 36 | 40 |
| Donor type | ||
| Unrelated donor | 51 | 57 |
| Sibling | 38 | 42 |
| Haploidentical donor | 1 | 1 |
| Stem cell source | ||
| PBSC | 81 | 90 |
| BM | 8 | 9 |
| dCB | 1 | 1 |
| Conditioning regimen | ||
| Reduced intensity | 77 | 86 |
| Full intensity | 13 | 14 |
| Clinical GI-GvHD grade at the time of biopsy | ||
| no GvHD | 46 | 51 |
| Grade I | 27 | 30 |
| Grade II | 11 | 12 |
| Grade III | 5 | 6 |
| Grade IV | 1 | 1 |
| Lerner GI-GvHD grade at the time of biopsy | ||
| no GvHD | 43 | 48 |
| Grade 1 | 30 | 33 |
| Grade 2 | 12 | 13 |
| Grade 3 | 4 | 5 |
| Grade 4 | 1 | 1 |
MDS, myelodysplastic syndrome; MPN, myeloproliferative neoplasm; NHL, non-Hodgkin’s lymphoma; PBSC, peripheral blood stem cells; BM, bone marrow; dCB, double cord blood. Other diagnosis included aplastic anemia and Hodgkin’s lymphoma.