| Drug 1 | |
|---|---|
| Generic/working name | Epacadostat |
| Company name | Incyte Corporation |
| Drug type | Small molecule |
| Drug class | IDO1 inhibitor |
| Dose | 100 |
| Unit | mg |
| Route | Oral (po) |
| Schedule of administration | Twice-daily (bid) |
| Drug 2 | |
|---|---|
| Generic/working name | Pembrolizumab |
| Company name | Merck & Co., Inc. |
| Drug type | Antibody |
| Drug class | Immunotherapy |
| Dose | 200 |
| Unit | mg |
| Route | Intravenous |
| Schedule of administration | Every 3 weeks for up to 35 infusions |
| Drug 3 | |
|---|---|
| Generic/working name | Pemetrexed |
| Company name | Generic |
| Drug type | Small molecule |
| Drug class | Antimetabolite |
| Dose | 500 |
| Unit | mg/m2 |
| Route | Intravenous |
| Schedule of administration | Day 1 of each 21-day cycle for a minimum of 4 cycles and a maximum of 6 cycles |
| Drug 4 | |
|---|---|
| Generic/working name | Carboplatin or cisplatin |
| Company name | Generic |
| Drug type | Platinum compound |
| Drug class | Alkylating agent |
| Dose/unit | Carboplatin AUC 5 or cisplatin 75 mg/m2 |
| Route | Intravenous |
| Schedule of administration | Day 1 of each 21-day cycle for a minimum of 4 cycles and a maximum of 6 cycles |