2. Drugs for the prevention of hereditary angioedema attacks.

Drug	Brand	Route of administration
Avoralstat	Not approved	Oral
Berotralstat	Orladeyo	Oral
C1‐INH(SC)	Haegarda	SC
C1‐INH‐nf	Cinryze	Intravenous
pdC1‐INH	Berinert	Intravenous
rhC1‐INH	Ruconest	Intravenous
Danazol	Danocrine/Cyclomen	Oral
Lanadelumab	Takhzyro	SC
Tranexamic acid	Lysteda	Oral

C1‐INH: C1 esterase inhibitor; C1‐INH‐nf: nanofiltered C1 esterase inhibitor; C1‐INH(SC): subcutaneous C1 esterase inhibitor; HAE: hereditary angioedema; pdC1‐INH: plasma‐derived C1 esterase inhibitor; rhC1‐INH: recombinant human C1 esterase inhibitor.