Table 2. Clinical characteristics and outcomes of DKA patients according to in-hospital mortality after DKA admission.
|
In-hospital mortality | P-value | ||
---|---|---|---|---|
|
|
|||
Age, years, median (IQR) | 28 (20-4 4) | 28 (20-41) | 63 (42-68) | 0.12a |
Sex | 0.08b | |||
Male, n (%) | 23 44.2) | 20 | 3 | |
DM diagnosis, n | 0.14b | |||
New DM diagnosis | 8 | 8 | 0 | |
DM1 | 35 | 34 | 1 | |
DM2 | 9 | 7 | 2 | |
APACHE II, points, mean ± SD | 11.8 ± 6.1 | 12.02 ± 6.44 | 17 ± 11.53 | 0.21a |
SOFA score, points, median (IQR) | 1.5 (0-3.25) | 1 (0-3) | 4 (1-4 ) | 0.23a |
No. of comorbidities, n (%) | 0.25b | |||
None | 21 | 20 | 1 | |
1 | 13 | 14 | 0 | |
2 or more | 16 | 14 | 2 | |
Infection | 0.08b | |||
No | 29 | 29 | 0 | |
Yes | 22 | 20 | 3 | |
DKA severity, n (%) | 1.00b | |||
Mild/moderate | 15 | 14 | 1 | |
Severe | 36 | 35 | 2 | |
pH, mean ± SD | 7.18 ± 0.15 | 7.17 ± 0.15 | 7.33 ± 0.07 | 0.07 a |
Excess base, mmol/l, mean ± SD | -18 ± 6.2 | -19.1 ± 6.13 | -12.1 ± 3.35 | 0.28a |
Serum potassium, millimole, mean ± SD | 4.95 ± 1.06 | 5.01 ± 1.04 | 3.93 ± 0.86 | 0.15a |
Serum anion gap, millimole, mean ± SD | 26.68 ± 8.65 | 26.92 ± 8.71 | 22.83 ± 7.95 | 0.47a |
Serum glucose, mg/dl, median (IQR) | 466 (393-639) | 459 (391-648) | 558 (423-640) | 0.70a |
Serum albumin, g/dl, median (IQR) | 4.00 (3.92-4.30) | 4.00 (4.00-4.35) | 3.50 (2.30-4.00) | 0.06a |
Osmolality, mOsm/kg, median (IQR) | 290 (283-304) | 290 (284-304) | 300 (283-304) | 0.52a |
Lactate, mmol/l, mean ± SD | 2.16 ± 1.12 | 2.18 ± 1.14 | 1.88 ± 0.83 | 0.66a |
Lactate, n (%) | 1.00b | |||
< 2 mmol/l | 28 | 26 | 2 | |
≥ 2 mmol/l | 24 | 23 | 1 | |
Lactate, n (%) | 1.00b | |||
< 4 mmol/l | 48 | 46 | 3 | |
≥ 4 mmol/l | 3 | 3 | 0 | |
Duration of DM, years, mean ± SD | 10.54 ± 9.66 | 10.23 ± 9.82 | 15.67 ± 5.13 | 0.13a |
Length of stay, days, median (IQR) | 5 (4.00-8.25) | 5 (4.00-8.00) | 21 (4.00-8.00) | 0.12a |
aMann-Whitney U or paired t test; bFisher exact test or likelihood ratio test; DKA = diabetic ketoacidosis; IQR = interquartile range; DM = diabetes mellitus; SD = standard deviation; SOFA = sequential organ failure assessment.