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. 2021 Feb 24;139(1):10–17. doi: 10.1590/1516-3180.2020.0285.R1.21102020

Table 2. Clinical characteristics and outcomes of DKA patients according to in-hospital mortality after DKA admission.

  • All patients

  • (n = 52)

In-hospital mortality P-value
  • Alive

  • (n = 49)

  • Dead

  • (n = 3)

Age, years, median (IQR) 28 (20-4 4) 28 (20-41) 63 (42-68) 0.12a
Sex 0.08b
Male, n (%) 23 44.2) 20 3
DM diagnosis, n 0.14b
New DM diagnosis 8 8 0
DM1 35 34 1
DM2 9 7 2
APACHE II, points, mean ± SD 11.8 ± 6.1 12.02 ± 6.44 17 ± 11.53 0.21a
SOFA score, points, median (IQR) 1.5 (0-3.25) 1 (0-3) 4 (1-4 ) 0.23a
No. of comorbidities, n (%) 0.25b
None 21 20 1
1 13 14 0
2 or more 16 14 2
Infection 0.08b
No 29 29 0
Yes 22 20 3
DKA severity, n (%) 1.00b
Mild/moderate 15 14 1
Severe 36 35 2
pH, mean ± SD 7.18 ± 0.15 7.17 ± 0.15 7.33 ± 0.07 0.07 a
Excess base, mmol/l, mean ± SD -18 ± 6.2 -19.1 ± 6.13 -12.1 ± 3.35 0.28a
Serum potassium, millimole, mean ± SD 4.95 ± 1.06 5.01 ± 1.04 3.93 ± 0.86 0.15a
Serum anion gap, millimole, mean ± SD 26.68 ± 8.65 26.92 ± 8.71 22.83 ± 7.95 0.47a
Serum glucose, mg/dl, median (IQR) 466 (393-639) 459 (391-648) 558 (423-640) 0.70a
Serum albumin, g/dl, median (IQR) 4.00 (3.92-4.30) 4.00 (4.00-4.35) 3.50 (2.30-4.00) 0.06a
Osmolality, mOsm/kg, median (IQR) 290 (283-304) 290 (284-304) 300 (283-304) 0.52a
Lactate, mmol/l, mean ± SD 2.16 ± 1.12 2.18 ± 1.14 1.88 ± 0.83 0.66a
Lactate, n (%) 1.00b
< 2 mmol/l 28 26 2
≥ 2 mmol/l 24 23 1
Lactate, n (%) 1.00b
< 4 mmol/l 48 46 3
≥ 4 mmol/l 3 3 0
Duration of DM, years, mean ± SD 10.54 ± 9.66 10.23 ± 9.82 15.67 ± 5.13 0.13a
Length of stay, days, median (IQR) 5 (4.00-8.25) 5 (4.00-8.00) 21 (4.00-8.00) 0.12a

aMann-Whitney U or paired t test; bFisher exact test or likelihood ratio test; DKA = diabetic ketoacidosis; IQR = interquartile range; DM = diabetes mellitus; SD = standard deviation; SOFA = sequential organ failure assessment.