Table 4. Performance, sensitivity, specificity, likelihood ratios and predictive values of PMEWS, CURB-65 and STSS scores.
AUC | 95% CI | Sensitivity (%) | Specificity (%) | +LR | −LR | PPV | NPV | P | |
---|---|---|---|---|---|---|---|---|---|
Mortality | |||||||||
PMEWS ≥ 3 | 0.968 | 0.912-0.993 | 100 | 81.91 | 5.53 | 0.0 | 26.08 | 100.0 | < 0.001* |
CURB-65 ≥ 1 | 0.942 | 0.877-0.979 | 83.33 | 90.43 | 8.70 | 0.18 | 35.72 | 98.83 | < 0.001* |
STSS ≥ 1 | 0.962 | 0.903-0.990 | 83.33 | 93.62 | 13.06 | 0.18 | 45.46 | 98.87 | < 0.001* |
ICU admission | |||||||||
PMEWS ≥ 5 | 0.941 | 0.875-0.978 | 80 | 95.56 | 18 | 0.21 | 66.68 | 97.72 | < 0.001* |
CURB-65 ≥ 1 | 0.898 | 0.821-0.949 | 80 | 93.33 | 12 | 0.21 | 57.13 | 97.67 | < 0.001* |
STSS ≥ 1 | 0.878 | 0.798-0.935 | 90 | 72.22 | 3.24 | 0.14 | 26.46 | 98.48 | < 0.001* |
Need for MV | |||||||||
PMEWS ≥ 5 | 0.854 | 0.769-0.917 | 60 | 96.47 | 17 | 0.41 | 74.99 | 93.18 | < 0.001* |
CURB-65 ≥ 1 | 0.867 | 0.785-0.927 | 66.67 | 95.29 | 14.17 | 0.35 | 71.4 | 94.18 | < 0.001* |
STSS ≥ 1 | 0.820 | 0.731-0.890 | 80 | 74.12 | 3.09 | 0.27 | 35.29 | 95.45 | < 0.001* |
PMEWS = Pandemic Medical Early Warning Score; CURB-65 = Confusion, Uremia, Respiratory rate, Blood pressure and age ≥ 65; STSS = Simple Triage Scoring System; AUC = area under the curve; CI = confidence interval; +LR = positive likelihood ratio; -LR = negative likelihood ratio; PPV = positive predictive value; NPV = negative predictive value; ICU = intensive care unit; MV = mechanical ventilation.
*P < 0.05 was considered significant.