Table 6.
Correlation between OI genotypes and echocardiographic parameters.
| Dependent variable β | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Independent variable | PAO | MPA | LAD | LVEDd | RVEDd | IVST | LVPWT | LVM | LVEF |
| OI | 0.409 | 2.279*** | 4.550*** | 3.352*** | 1.772 | -0.781 | -0.915 | -1.321 | -3.424** |
| COL1A1 mutation | 0.226 | 1.557** | 3.915*** | 2.714** | 0.978 | -0.389 | -0.431 | 1.316 | -3.249** |
| COL1A2 mutation | 0.612 | 1.027 | 1.967 | 1.218 | -0.440 | -0.366 | -0.396 | -2.675 | 0.834 |
| Other genes mutations | 0.327 | 1.761 | 1.334 | 2.391 | 2.783 | -0.415 | -0.497 | -1.488 | -1.845 |
OI, osteogenesis imperfecta; BSA, body surface area; PAO, proximal ascending aorta; MPA, main pulmonary artery; LAD, left atrial anteroposterior dimension; LVEDd, left ventricular end-diastolic dimension; RVEDd, right ventricular end-diastolic dimension; IVST, interventricular septal wall thickness; LVPWT, left ventricular posterior wall thickness; LVM, left ventricular mass; LVEF, left ventricular ejection fraction.
β, Regression coefficient. Adjusted for age, gender, and BSA.
*P < 0.05; **P < 0.01; ***P < 0.001.