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. 2022 Oct 20;13:1004946. doi: 10.3389/fendo.2022.1004946

Table 6.

Correlation between OI genotypes and echocardiographic parameters.

Dependent variable β
Independent variable PAO MPA LAD LVEDd RVEDd IVST LVPWT LVM LVEF
OI 0.409 2.279*** 4.550*** 3.352*** 1.772 -0.781 -0.915 -1.321 -3.424**
COL1A1 mutation 0.226 1.557** 3.915*** 2.714** 0.978 -0.389 -0.431 1.316 -3.249**
COL1A2 mutation 0.612 1.027 1.967 1.218 -0.440 -0.366 -0.396 -2.675 0.834
Other genes mutations 0.327 1.761 1.334 2.391 2.783 -0.415 -0.497 -1.488 -1.845

OI, osteogenesis imperfecta; BSA, body surface area; PAO, proximal ascending aorta; MPA, main pulmonary artery; LAD, left atrial anteroposterior dimension; LVEDd, left ventricular end-diastolic dimension; RVEDd, right ventricular end-diastolic dimension; IVST, interventricular septal wall thickness; LVPWT, left ventricular posterior wall thickness; LVM, left ventricular mass; LVEF, left ventricular ejection fraction.

β, Regression coefficient. Adjusted for age, gender, and BSA.

*P < 0.05; **P < 0.01; ***P < 0.001.