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. 2022 Oct 17;9:1013466. doi: 10.3389/fnut.2022.1013466

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Copyright © 2022 Huang, Huang, Chen, Huang, Liu, Jia and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Statistical Spearman’s correlations between the characteristic intestinal microbes and the biochemical indexes in T2DM mice. (A) Hierarchical clustering heatmap of the correlation between the characteristic intestinal microbes and the biochemical indexes. The chocolate and orchid nodes represent the positive and negative correlation coefficient, respectively; the color shades indicate the strength of correlation. (B) Visualization of the correlation network. Green, blue, and yellow nodes represent the characteristic intestinal microbes, biochemical indexes, and fecal SCFAs, respectively; the solid red lines and dotted blue lines indicate the correlation coefficient >0.6 (p < 0.01) and the correlation coefficient <–0.6 (p < 0.01), respectively. The linewidth reflects on the strength of correlation.