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. 2022 Oct 20;13:982887. doi: 10.3389/fimmu.2022.982887

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Copyright © 2022 Begue, Waerlop, Salaun, Janssens, Bellamy, Cox, Davies, Gianchecchi, Medaglini, Montomoli, Pettini, Leroux-Roels, Clement and Pagnon

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pilot Study 1: Evaluation of data from each of the participating laboratories. Each dot represents the A/California/07/2009 stimulated and background subtracted % of parent cells for a single sample. The red line indicates the mean of the 24 samples for each outcome for each laboratory. All 0 values were replaced by 0.00001 in order to represent the data. Seven laboratories participated in pilot study 1, however one laboratory did not provide data in time for inclusion in the assessment of the results. IFN, interferon; IL, interleukin; TNF, tumor necrosis factor.