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. 2022 Nov 3;17(11):e0275258. doi: 10.1371/journal.pone.0275258

Fig 1. Leonurine enhanced cardiac function in rats with ISO-induced heart failure by improving haemodynamic variables.

Fig 1

Cardiac function is responsive to haemodynamic variables, including LVSP, LVEDP, -dP/dt max, and +dP/dt max. Leonurine increased (A) LVSP level, and decreased levels of (B) LVEDP, (C) -dP/dt max, and (D) +dP/dt max compared with the model group. ##P<0.01, control group vs. model group; **P<0.01, *P<0.05, leonurine groups vs. model group. LVSP, left ventricular systolic pressure; LVEDP, left ventricular end-diastolic pressure; -dP/dt max, the falling rate of LVEDP; +dP/dt max, the rising rate of LVEDP.