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. 2022 Nov 3;17(11):e0275258. doi: 10.1371/journal.pone.0275258

Fig 4. Leonurine reduced the expression of proteins related to fibrosis in heart tissues from rats with ISO-induced heart failure.

Fig 4

(A) Compared to ISO-induced rats, leonurine decreased the expression of proteins related to fibrosis including (B) FN1, (C) α-SMA, and (D) COL3A1. ##P<0.01, ###P<0.001, model group vs. control group; **P<0.01, leonurine groups vs. model group.