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(A) Compared to ISO-induced rats, leonurine decreased expressions of pyroptosis proteins including (B) GSDMD, (C) cleaved GSDMD, (D) Caspase 1, (E) cleaved Caspase 1, and the level of (F) IL-1β in plasma. #P<0.05, ##P<0.01, ###P<0.001, model group vs. control group; *P<0.05, **P<0.01, ***P<0.001, leonurine groups vs. model group.
