Table 4.
Cox proportional hazards regression model for mortality
| Characteristic | HR | 95% CI | p-value |
|---|---|---|---|
| Age | 1.05 | 1.01, 1.08 | 0.010 |
| Chronic kidney disease | 1.09 | 0.42, 2.81 | 0.861 |
| SOFA score | 1.44 | 1.23, 1.68 | 3.59e-06 |
| Vancomycin administration | 0.41 | 0.17, 1.00 | 0.051 |
| Admission location | |||
| Emergency department | – | – | |
| Hospital medicine | 1.49 | 0.59, 3.73 | 0.399 |
| Outside hospital | 0.18 | 0.04, 0.86 | 0.032 |
| Microbiome metabolic profile | 1.65 | 1.18, 2.31 | 0.003 |
Variables with unadjusted p-values < 0.3 from the univariate analysis (Table 2) were included in the multivariate analysis. Unadjusted p-values were obtained from a likelihood ratio test and reported as exact values (n = 68 independent samples from patients).
HR hazard ratio, CI confidence interval.