Table 2. Lipid compositions used to prepare multilamellar vesicles (MLVs).
| MLVs with (–1) charged lipids | |||
|---|---|---|---|
| MLVs (equivalent charge %) | 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-l-serine/1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)/phosphatidylinositol (PI) (mol %) | Cholesterol (mol %) | 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) (mol %) |
| PS/PG/PI (0 %) | 0 | 20 | 80 |
| PS/PG/PI (20 %) | 20 | 20 | 60 |
| PS/PG/PI (40 %) | 40 | 20 | 40 |
| PS/PG/PI (60 %) | 60 | 20 | 20 |
| PS/PG/PI (80 %) | 80 | 20 | 0 |
| MLVs with (–2.5) charged lipid | |||
| MLVs (equivalent charge %) | PI(4)P (mol %) | Cholesterol (mol %) | POPC (mol %) |
| PI(4)P (0 %) | 0 | 20 | 80 |
| PI(4)P (20 %) | 8 | 20 | 72 |
| PI(4)P (40 %) | 16 | 20 | 64 |
| PI(4)P (60 %) | 24 | 20 | 56 |
| PI(4)P (80 %) | 32 | 20 | 48 |
| MLVs with (–4) charged lipid | |||
| MLVs (equivalent charge %) | PI(4,5)P2 (mol %) | Cholesterol (mol %) | POPC (mol %) |
| PI(4,5)P2 (0 %) | 0 | 20 | 80 |
| PI(4,5)P2 (20 %) | 5 | 20 | 75 |
| PI(4,5)P2 (40 %) | 10 | 20 | 70 |
| PI(4,5)P2 (60 %) | 15 | 20 | 65 |
| PI(4,5)P2 (80 %) | 20 | 20 | 60 |