Table 2.
Univariate and multivariate analysis of survival with PG-DLBCL.
| Variables | Overall survival | Cancer-specific survival | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |||||
| Log rank X2 | P | HR (95% CI) | P | Log rank X2 | P | HR (95% CI) | P | |
| Sex | 0.333 | 0.564 | 0.012 | 0.911 | ||||
| Female | ||||||||
| Male | ||||||||
|
| ||||||||
| Age (years) | 223.417 | 0.001 | 0.001 | 117.129 | 0.001 | 0.001 | ||
| <50 | Reference | Reference | ||||||
| 50–59 | 1.076 (0.720–1.607) | 0.722 | 1.027 (0.658–1.603) | 0.906 | ||||
| 60–69 | 1.848 (1.284–2.659) | 0.001 | 1.856 (1.245–2.766) | 0.002 | ||||
| 70–79 | 2.834 (1.983–4.052) | 0.001 | 2.143 (1.433–3.206) | 0.001 | ||||
| ≥80 | 4.223 (2.966–6.013) | 0.001 | 3.225 (2.176–4.779) | 0.001 | ||||
|
| ||||||||
| Race | 8.717 | 0.013 | 0.001 | 8.260 | 0.016 | 0.003 | ||
| Black | Reference | Reference | ||||||
| White | 0.633 (0.482–0.830) | 0.001 | 0.612 (0.450–0.831) | 0.002 | ||||
| Others | 0.501 (0.349–0.718) | 0.001 | 0.523 (0.349–0.786) | 0.002 | ||||
|
| ||||||||
| Marital status | 54.196 | 0.001 | 36.632 | 0.001 | ||||
| Married | Reference | Reference | ||||||
| Unmarried/single | 1.492 (1.257–1.771) | 0.001 | 1.472 (1.206–1.796) | 0.001 | ||||
|
| ||||||||
| Insurance | 16.042 | 0.001 | 0.006 | 13.208 | 0.001 | 0.017 | ||
| Insured | Reference | Reference | ||||||
| Any medicaid | 1.362 (1.100–1.686) | 0.005 | 1.345 (1.054–1.716) | 0.017 | ||||
| Uninsured | 0.724 (0.423–1.240) | 0.724 | 0.681 (0.374–1.241) | 0.210 | ||||
|
| ||||||||
| Ann Arbor stage | 31.392 | 0.001 | 0.001 | 51.234 | 0.001 | 0.001 | ||
| I | Reference | Reference | ||||||
| II | 1.452 (1.156–1.823) | 0.001 | 1.526 (1.161–2.006) | 0.002 | ||||
| III | 1.828 (1.354–2.469) | 0.001 | 1.996 (1.400–2.845) | 0.001 | ||||
| IV | 2.159 (1.758–2.650) | 0.001 | 2.760 (2.176–3.501) | 0.001 | ||||
|
| ||||||||
| Surgery | 1.967 | 0.161 | 0.665 | 0.415 | ||||
| No | Reference | Reference | ||||||
| Yes | 1.013 (0.774–1.325) | 0.925 | 0.731 (0.531–1.006) | 0.054 | ||||
|
| ||||||||
| Chemotherapy | 278.954 | 0.001 | 203.315 | 0.001 | ||||
| No/unknown | Reference | Reference | ||||||
| Yes | 0.315 (0.260–0.380) | 0.001 | 0.296 (0.239–0.367) | 0.001 | ||||
|
| ||||||||
| Radiation | 23.686 | 0.001 | 19.663 | 0.001 | ||||
| No/unknown | Reference | Reference | ||||||
| Yes | 0.665 (0.511–0.865) | 0.002 | 0.656 (0.479–0.900) | 0.009 | ||||
Note. Univariate analysis: Kaplan–Meier analysis; multivariate analysis: cox regression analysis; HR: hazard ratio.