Table 2. VTE risk factors present within the 3 mo preceding VTE diagnosis.
| Risk factor, n (%) | VKA ( N = 3,043) | DOAC ( N = 4,991) |
|---|---|---|
| Acute medical illness a | 218 (7.2) | 214 (4.3) |
| Hospitalization a | 367 (12.1) | 483 (9.7) |
| Long-haul travelling a | 168 (5.5) | 286 (5.7) |
| Surgery a | 345 (11.3) | 617 (12.4) |
| Trauma of the lower limb a | 212 (7.0) | 443 (8.9) |
| Active cancer | 144 (4.7) | 264 (5.3) |
| Pregnancy | 55 (1.8) | 31 (0.6) |
| Recent bleed or anemia | 129 (4.2) | 106 (2.1) |
| Chronic heart failure | 132 (4.3) | 121 (2.4) |
| Chronic immobilization | 183 (6.0) | 206 (4.1) |
| Family history of VTE | 192 (6.3) | 354 (7.1) |
| History of cancer | 285 (9.4) | 493 (9.9) |
| Hormone replacement therapy (females) | 46 (1.5) | 82 (1.6) |
| Known thrombophilia | 85 (2.8) | 144 (2.9) |
| Oral contraception (females) | 143 (4.7) | 316 (6.3) |
| Prior episode of DVT and/or PE | 514 (16.9) | 795 (15.9) |
| Renal insufficiency | 179 (5.9) | 107 (2.1) |
Abbreviations: DOAC, direct oral anticoagulant; DVT, deep vein thrombosis; VKA, vitamin K antagonist; VTE, venous thromboembolism.
a
Provoking factors.