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. 2022 Oct 21;16(5):799–811. doi: 10.31616/asj.2022.0367

Table 3.

The NOMS decision framework

Neurologic (N) Oncologic (O) Mechanical (M) Systemic (S) Decision
Low-grade ESCC+no myelopathy Radiosensitive Stable cEBRT
Radiosensitive Unstable Stabilization followed by cEBRT
Radioresistant Stable SRS
Radioresistant Unstable Stabilization followed by SRS
High-grade ESCC±myelopathy Radiosensitive Stable cEBRT
Radiosensitive Unstable Stabilization followed by cEBRT
Radioresistant Stable Able to tolerate surgery Decompression/stabilization followed by SRS
Radioresistant Stable Unable to tolerate surgery cEBRT
Radioresistant Unstable Able to tolerate surgery Decompression/stabilization followed by SRS
Radioresistant Unstable Unable to tolerate surgery Stabilization followed by cEBRT

Adapted from Chang SY, et al. Orthop Surg 2019;11:552-9 [35].

NOMS, neurologic, oncologic, mechanical, and systemic; ESCC, epidural spinal cord compression; cEBRT, conventional external beam radiation; SRS, stereotactic radiosurgery.