Table 2.
Age-Stratified ET and ET-Plus Classifications of Probands, First-degree and Second-degree Relatives
| Probands (n=84) | 1st-degree Relatives (n=182) | 2nd-degree Relatives (n=48) | |
|---|---|---|---|
| All ages | |||
| ET | 21 (27.3) | 24 (13.6) | 12 (25.0) |
| ET-Plus | 56 (72.7) | 66 (37.5) | 9 (18.8) |
| Normal | 0 (00.0) | 86 (48.9) | 27 (56.3) |
| Not classifieda | 7 | 6 | 0 |
| pb | 0.001 | 0.001 | 0.001 |
| 0–40 yrs | |||
| ET | 1 (100.0) | 2 (10.0) | 10 (38.5) |
| ET-Plus | 0 (00.0) | 3 (15.0) | 2 (07.7) |
| Normal | 0 (00.0) | 15 (75.0) | 14 (53.8) |
| Not classifieda | 0 | 0 | 0 |
| 41–50 yrs. | |||
| ET | 1 (33.3) | 8 (27.6) | 0 (00.0) |
| ET-Plus | 2 (66.7) | 5 (17.2) | 0 (00.0) |
| Normal | 0 (00.0) | 16 (55.2) | 7 (100.0) |
| Not classifieda | 0 | 0 | 0 |
| 51–60 yrs. | |||
| ET | 5 (45.5) | 7 (17.1) | 1 (14.3) |
| ET-Plus | 6 (54.5) | 9 (22.0) | 2 (28.6) |
| Normal | 0 (00.0) | 25 (61.0) | 4 (57.1) |
| Not classifieda | 1 | 0 | 0 |
| 61–70 yrs. | |||
| ET | 10 (31.3) | 5 (11.1) | 1 (16.7) |
| ET-Plus | 22 (68.8) | 23 (51.1) | 4 (66.7) |
| Normal | 0 (00.0) | 17 (37.8) | 1 (16.7) |
| Not classifieda | 1 | 1 | 0 |
| 71+ yrs. | |||
| ET | 4 (13.3) | 2 (04.9) | 0 (00.0) |
| ET-Plus | 26 (86.7) | 26 (63.4) | 1 (50.0) |
| Normal | 0 (00.0) | 13 (31.7) | 1 (50.0) |
| Not classifieda | 5 | 5 | 0 |
a
Enrollees who met criteria for ET, but cannot be classified regarding ET-plus due to missing data. These cases are not included in calculation of percentages.
b
Chi-square tests comparing ET, ET-plus, and normal frequencies within group. Bolded p values are significant at p < 0.05.
Values are frequencies (column percentages).