Table 1.
Demographic Values and Rates for All Herpes Simplex Encephalitis (HSE) (Primary Diagnosis Only) Hospitalizations in the United States per Year
| All Hospitalizationsa | HSE Primary Diagnosis b | Rate of HSE Cases per 100 000 | |||||
|---|---|---|---|---|---|---|---|
| Total n | Weighted n | % | HSE n | Weighted n | % | ||
| 95 068 178 | 207 468 667 | 100 | 4577 | 10 272 | 100 | 4.95 | |
| Gender | |||||||
| Male | 39374914 | 85 922 943 | 41.4 | 2230 | 5032 | 49.0 | 5.86 |
| Female | 55 693 264 | 121 545 724 | 58.6 | 2347 | 5242 | 51.0 | 4.31 |
| Age (continuous) | |||||||
| Age, mean | 56.0 | … | … | 59.9 | … | … | … |
| Age (categorical) | |||||||
| 1–17 | 3 034 721 | 9 174 432 | 4.4 | 139 | 421 | 4.1 | 4.59 |
| 18–44 | 26 462 071 | 57 808 211 | 27.9 | 736 | 1576 | 15.3 | 2.73 |
| 45–64 | 26 777 643 | 57 777 828 | 27.8 | 1569 | 3598 | 35.0 | 6.23 |
| ≥65 | 38 793 743 | 82 708 199 | 39.9 | 2133 | 4677 | 45.5 | 5.65 |
| Primary payorc | |||||||
| Medicare/Medicaid | 61 289 069 | 132 303 789 | 63.8 | 2741 | 6034 | 58.7 | 4.56 |
| Private | 26 105 284 | 58 053 657 | 28.0 | 1453 | 3369 | 32.8 | 5.80 |
| Uninsured/other | 76 58 215 | 17 081 738 | 8.2 | 383 | 871 | 8.5 | 5.10 |
| Discharge dispositiond | |||||||
| Home or self care | 64 324 591 | 141 658 473 | 68.3 | 1572 | 3488 | 34.0 | 2.46 |
| Transfer, home health | 27 215 115 | 58 469 192 | 28.2 | 2616 | 5883 | 57.3 | 10.06 |
| Against medical advice | 1 318 245 | 2 652 412 | 1.3 | 45 | 85 | 0.8 | 3.20 |
| Other | 40 752 | 74 241 | 0.0 | 4 | 7 | 0.1 | 9.43 |
| Death | 2 120 875 | 4 513 341 | 2.2 | 337 | 804 | 7.8 | 17.81 |
| Hospitalization | |||||||
| Length of stay, mean | 4.9 | … | … | 13.5 | … | … | … |
aHospitalizations and HSE cases exclude the last 60 days of each data set and are ≥1 year of age.
bHSE as primary diagnosis indicated by the first listed diagnosis, either “543” for International Classification Diagnosis Code, ninth edition or “B004,” “B100*” for the tenth edition. HSE cases in this table are not the same as index cases.
cPayor groups: Medicare/Medicaid = includes both fee-for-service and managed care patients; private = includes commercial carriers and private health maintenance organizations (HMOs)/preferred provider organizations (PPOs); uninsured/other = includes worker’s compensation, CHAMPUS, CHAMPVA, Title V, and other government programs.
dTransfer includes short-term hospitals, skilled nursing facility, or intermediate care facility.