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. 2022 Jun 30;162(4):899–919. doi: 10.1016/j.chest.2022.06.026

Table 4.

Adverse Events and Serious Adverse Events

Type of Event INCS Placebo
Adverse events, total
 Asthma exacerbation 3 18
 Lower respiratory tract 8 6
 Upper respiratory tract (including ears) 67 90
 Cough 15 11
 GI tract 11 12
 Dehydration 3 1
 ADHD diagnosis 3 4
 Other infections (not included in other listed categories) 17 40
 Hypersomnolence 1 2
 Sleep apnea symptom exacerbation 0 6
 Other 27 34
 Total 155 224
Serious adverse events
 Asthma 0 3
 Lower respiratory tract 1 0
 Total 1 4

ADHD = attention-deficit/hyperactivity disorder; INCS = intranasal corticosteroids.